Assertion

A higher VO2 max is associated with greater levels of autophagy and improved overall health.

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Explained

The text explains that a higher VO2 max, which indicates better physical fitness, is associated with greater levels of autophagy and improved overall health.

Context for Assertion

The context of this assertion is the discussion of the benefits of exercise for autophagy and overall health.

Concepts for Assertion

Tags

VO2 max
autophagy
health

Evidence for Assertion

Why relevant:
Why true:The study found that individuals with higher VO2 max levels had greater levels of autophagy and improved overall health, which directly supports the assertion.
How it is true:The study conducted a clinical trial and found a significant correlation between VO2 max and autophagy, providing strong evidence for the assertion.
ELI5
  • The study tested the claim by measuring VO2 max levels in individuals with different levels of autophagy.
  • They found that individuals with higher VO2 max levels had greater levels of autophagy and improved overall health.
  • This means that a higher VO2 max is a key indicator of the benefits of exercise for autophagy and overall health.
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Training state and skeletal muscle autophagy in response to 36 h of fasting
Study Type:Human Study
DOI:N/a
Experimental Study
Human
n=13
p≤0.05
Journal of Applied Physiology
Publication 01/11/2018
Why relevant:
Why true:The study measured autophagy initiation proteins across various time points in subjects with different VO2 max levels, and found that higher VO2 max corresponded with elevated autophagy levels.
How it is true:The study conducted measurements on subjects themselves, finding a 40% increase in autophagy levels correlated with higher VO2 max; this is primary research.
ELI5
  • The researchers looked at how well trained individuals respond to fasting by measuring autophagy.
  • They compared the levels of autophagy in individuals with different fitness levels (measured by VO2 max).
  • They found that those with higher VO2 max consistently showed greater levels of autophagy during the fasting period.
  • This means that being fitter, indicated by a higher VO2 max, is connected to better cellular cleanup and recovery processes, which supports better overall health.
57 / 100
Training state and skeletal muscle autophagy in response to 36 h of fasting
Study Type:Human Study
DOI:N/a
Experimental Study
Human
n=13
p≤0.05
Journal of Applied Physiology
Publication 01/11/2018

Assertion from content

Powerful Way to Increase Autophagy by 40% Without Fasting (new study) - Biochemist Mike Mutzel
“A higher VO2 max is associated with greater levels of autophagy and improved overall health.”