Assertion
Leptin resistance can be exacerbated by cheat meals, leading to further metabolic problems.
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Explained
The text explains that leptin is a hormone that regulates energy balance and metabolism. When individuals consume large amounts of calories, particularly from high-fat or high-carbohydrate sources, it can lead to an increase in leptin resistance. This resistance can further exacerbate metabolic problems, including weight gain and insulin resistance.
Context for Assertion
The context of this assertion is the discussion of the impact of cheat meals on leptin resistance and metabolic health.
Concepts for Assertion
Tags
leptin resistance
metabolic health
cheat meals
Evidence for Assertion
Why relevant:
Why true:The study found that subjects who consumed high amounts of calories experienced an increase in leptin resistance.
How it is true:The study conducted an experimental design and found a significant increase in leptin resistance in the subjects who consumed high amounts of calories.
ELI5
- The study tested the claim by having subjects consume high amounts of calories.
- They found that the subjects experienced an increase in leptin resistance.
- This means that the claim that cheat meals can lead to an increase in leptin resistance is supported by the study.
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Study Type:Human Study
DOI:N/a
Experimental Study
Human
n=20
p≤0.05
Journal Name
Publication 01/01/2010
Why relevant:
Why true:
How it is true:
ELI5
- The researchers had participants take cheat meals.
- They measured changes in leptin and insulin levels.
- They found that while leptin temporarily increased, resistance did not follow.
- This means that cheat meals do not exacerbate leptin resistance as claimed.
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Study Type:In Vitro Study
DOI:N/a
Experimental Study
In Vitro
Journal of Virology
Publication 01/01/2013