Health Claims

Taking a drug called retatrutide can shrink your waist by nearly 8 inches over a year if you're an adult with obesity, which means you're losing dangerous belly fat that's linked to heart and metabolic problems.

A drug called retatrutide, taken once a week, helped lower blood sugar a lot in people with type 2 diabetes over 9 months — more than a placebo or another diabetes drug.

A shot called retatrutide, given once a week, helped people with obesity lose nearly a quarter of their body weight over a year—some losing around 57 pounds—much more than those on a dummy shot.

Taking a drug that turns on the glucagon receptor for a long time might affect how the body manages energy and fat, but scientists aren't totally sure how it works yet.

Blocking the glucagon signal in people with type 2 diabetes might cause weight gain, more fat in the liver, and higher blood fat levels — suggesting this hormone helps control how the body uses energy and fat.

Some new weight-loss drugs that work on two hormone receptors at once seem to help people lose a lot of weight and also improve liver health in those with fatty liver disease, based on early studies.

People taking higher doses of tirzepatide are more likely to stop using it because of side effects, even though it works better at those doses.

Tirzepatide doesn’t cause more serious health problems than a placebo in adults, even though it can cause mild stomach issues — overall, it seems safe to use for several months.

People taking tirzepatide are more likely to get stomach issues like nausea, vomiting, or constipation than those on a sugar pill, especially at higher doses — but most of these side effects aren’t severe.

People with obesity or type 2 diabetes who take tirzepatide are much more likely to lose a meaningful amount of weight—like 5%, 10%, or even 15% of their body weight—compared to those who don’t, and the more they take, the better the results seem to be.

People with obesity or type 2 diabetes who took a drug called tirzepatide lost a lot of weight—more when they took higher doses—and the effect lasted up to about three years.

A new kind of weight-loss drug that mixes a GLP-1 drug with a different kind of molecule might help people lose 14% of their weight in just three months.

Mixing a weight-loss drug with another drug that builds muscle might help people lose fat without losing muscle, which could be healthier in the long run.

About half of people who start taking GLP-1 drugs for weight loss stop within a year because of side effects like nausea or lack of support, even though they work well in studies.

A new weight-loss drug called retatrutide might help people with obesity lose about a quarter of their body weight in less than a year—and it could work even better and faster than weight-loss surgery or other medicines we have now.

A new weight-loss drug called tirzepatide might help people with obesity lose about 23% of their body weight in a year and a half — possibly even more than some weight-loss surgeries.

If you're losing weight with retatrutide but not eating enough protein or doing strength training, you might lose a lot of muscle because your body starts breaking it down.

A diabetes drug called tirzepatide can help people lose up to 21% of their body weight, but the weight loss tends to stop increasing too soon — especially for those with type 2 diabetes.

When a drug like semaglutide turns on certain brain and body signals, it helps people feel fuller, eat less, and lose about 15% of their body weight on average.

Blocking the hormone glucagon with drugs might actually make things worse for people — causing weight gain, higher blood pressure, and more liver fat.

Glucagon might help people eat less and lose weight on its own, even if it's not affecting blood sugar — but scientists used to ignore this idea because of old beliefs about how metabolism works.

Retatrutide keeps helping people lose weight steadily for a whole year without slowing down, while other weight-loss drugs like GLP-1s tend to stop working as well after a few months.

People with obesity and knee pain from arthritis who took a drug called retatrutide lost nearly a third of their body weight and felt much less pain—showing it might help both their weight and joint issues.

Turning on two specific body switches—one for glucagon and one for GLP-1—helps burn more energy without raising blood sugar, because one speeds up metabolism and the other keeps blood sugar in check.