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A drug called AMG 145 can lower a harmful blood protein linked to heart disease by up to 59% in people with high cholesterol who are already taking statins, and it seems to do more than just lower...
A drug called AMG 145, when given every two weeks, cuts bad cholesterol by about three-quarters in people with high cholesterol who are already on strong meds or have a genetic form of the condition...
A drug called AMG 145, when given as a weekly shot at 35 mg or more, can cut bad cholesterol by up to 81% in people already on cholesterol meds, and the effect lasts through the week—so it might work...
A shot of a drug called AMG 145 can quickly lower bad cholesterol—by up to 64% in just a few days—especially when given at higher doses, and it works by targeting a specific protein in the body.
People born with certain gene changes that lower their bad cholesterol over their whole life have a lower chance of heart disease — the more their cholesterol is lowered, the lower their risk.
People who naturally have lower 'bad' cholesterol because of their genes tend to have cleaner arteries, which means less buildup of plaque over time.
People born with a certain gene that lowers their bad cholesterol their whole life have a lower risk of heart disease than what we'd expect from cholesterol-lowering drugs like statins — meaning...
White adults with a certain gene variant have lower bad cholesterol and are nearly half as likely to get heart disease over 15 years — showing that even a small, lifelong drop in cholesterol can...
Black adults with a certain genetic mutation have much lower bad cholesterol and are way less likely to get heart disease over 15 years — this shows that keeping cholesterol low from an early age...
A specific part of the PCSK9 protein (the tail end) is needed to ship it out of liver cells; if this part is broken, less PCSK9 gets into the blood, so cholesterol stays lower.
Some cholesterol-lowering drugs called PCSK9 inhibitors can lower a specific type of blood fat linked to heart disease, and that might help protect people with high levels, but scientists aren't sure...
Blocking a protein called PCSK9 helps the immune system better recognize and attack cancer cells in mice, slowing tumor growth — and it works in a way that's not related to cholesterol.
A type of medicine (like evolocumab or alirocumab) blocks a protein in your body called PCSK9, which helps your liver remove bad cholesterol from your blood—cutting it by about half.
A protein called PCSK9 helps break down the liver's 'LDL cholesterol cleaners,' so more bad cholesterol stays in your blood, raising heart disease risk. People with certain PCSK9 gene changes either...
Genes have a bigger influence on how much people sit at work than on how much they sit during free time.
Just because someone sits a lot doesn’t mean they’re genetically wired to be less active — sitting and moving aren’t exact opposites in our DNA, even though they’re somewhat linked in behavior.
How much you say you sit and how much you actually sit are somewhat linked — about 1 in 3 people who report sitting a lot really do. And nearly half of that link comes from shared genes, meaning your...
People's genes seem to play a smaller role in how they report their sitting time compared to their actual sitting habits — meaning how much you say you sit isn't as influenced by DNA as how much you...
More than half of why people sit or recline different amounts every day comes down to their genes, not just their habits or surroundings.
IGF-1 helps build muscle by turning on growth signals inside cells, and the IGF-1 made in the muscle itself might matter more than the kind that comes from the liver.
Lifting weights makes your body release more growth hormone, especially when you do medium-heavy sets with short breaks. This effect is weaker in older people.
When women work out during the part of their cycle when estrogen is high, they might build more muscle because estrogen helps protect muscles and speed up recovery.
In young men, how sensitive their muscles are to testosterone—measured by androgen receptor levels—matters more for muscle growth than how much testosterone is in their blood.
When men lift weights, their testosterone helps their muscles grow by turning on certain signals in the muscle cells. This hormone response can last up to two days after a workout, making muscles...