Browse evidence-based analysis of health-related claims and assertions
After damaging the inner optic nerve head tissue with enzymes, adding saline solution slightly increased stiffness by about 13% compared to the damaged state.
Quantitative
After damaging the inner optic nerve head tissue with enzymes, the special peptide restored stiffness by nearly 50% compared to the damaged state.
In the inner part of the eye's optic nerve head, collagen-breaking enzymes caused a 57% drop in stiffness compared to normal.
After damaging the eye tissue with enzymes, adding a saline solution (vehicle) made the stiffness drop even more by about 26% compared to the damaged state.
After damaging the eye tissue with collagen-breaking enzymes, applying a special peptide helped restore some stiffness, increasing it by about 23% compared to the damaged state.
When rats' eye tissue was treated with an enzyme that breaks down collagen, the stiffness of the outer part of the eye decreased by almost 40% compared to normal.
When airway muscle cells are grown with allergen-activated asthma eosinophils, the fluid around them has about 50% more TGF-β1 protein than when grown with non-activated eosinophils.
Eosinophils from asthma patients already produce more TGF-β1 protein than healthy people even before allergen exposure.
In asthma patients, the number of eosinophils in blood increases from 0.34 to 0.52 billion per liter within 24 hours after allergen exposure.
In asthma patients, the number of eosinophils in sputum nearly doubles from 5.5% to 13.3% within 24 hours after allergen exposure.
Blocking eosinophil adhesion molecules with RGDS peptide reduces collagen and fibronectin gene activity in airway muscle cells to levels seen with healthy eosinophils.
Whether asthma eosinophils are activated by allergens or not, they don't change the activity of the WNT-5A gene in airway muscle cells.
Descriptive
Airway muscle cells grown with allergen-activated asthma eosinophils produce nearly 5 times more fibronectin gene activity than when grown with healthy eosinophils.
Airway muscle cells grown with allergen-activated asthma eosinophils produce over 5 times more collagen I gene activity than when grown with healthy eosinophils.
When airway muscle cells are grown with allergen-activated asthma eosinophils, the fluid around them has about twice as much TGF-β1 protein as when grown with healthy eosinophils.
When eosinophils from asthma patients are exposed to allergens, they produce about 1.58 times more TGF-β1 protein compared to before exposure, which may contribute to inflammation.
When older men with muscle loss take collagen supplements during strength training, gaining muscle is more closely linked to losing fat compared to those taking a placebo.
Correlational
Taking collagen supplements while doing strength training is safe for older men with muscle loss, with no health issues found in the study.
Balance and coordination get better with strength training for older men with muscle loss, but collagen supplements don't make it better than training alone.
Strength training boosts bone mass in older men with muscle loss, but adding collagen supplements doesn't make it better than just training alone.
Strength in the quadriceps muscles improves more (16.5 Nm) in older men with muscle loss who take collagen supplements during strength training than those taking a placebo (7.3 Nm).
Causal
Older men with muscle loss who take collagen supplements during strength training lose more body fat (5.4 kg) than those taking a placebo (3.5 kg).
Older men with muscle loss who do strength training and take collagen supplements gain more muscle mass (4.2 kg) than those taking a placebo (2.9 kg).
Muscle growth requires a supportive infrastructure of tendons, fascia, and cartilage to withstand mechanical loading.
Assertion