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Fat-derived particles from obese individuals cause breast cancer cells to reorganize their energy-producing mitochondria toward the edges of the cell, and this reorganization depends on leptin...
Fat-derived particles from obese individuals reprogram breast cancer cells to burn fat for energy instead of sugar, reducing sugar breakdown byproducts and increasing production of molecules used for...
Tiny particles from fat tissue in obese people help triple-negative breast cancer cells survive stress by blocking early cell death, and this protection disappears when leptin signaling is blocked.
Fat tissue from obese individuals releases tiny particles that make triple-negative breast cancer cells move faster, invade deeper, and form more colonies, and blocking the leptin receptor stops this...
Eating a diet that reduces inflammation may strengthen the impact of muscle-derived signaling molecules on metabolism, immune function, and brain health.
Proteins released by muscles during activity, such as IL-6, irisin, BDNF, IL-15, and myostatin, influence processes related to metabolism, immune response, and brain function in humans.
Muscles release specific signaling molecules called myokines that communicate with the liver, brain, and gut microbiota to regulate their function.
Extracellular vesicles released by fat tissue in obese individuals can increase the aggressive behavior of breast cancer cells by changing their internal functions, decreasing proteins that maintain...
In people with peripheral arterial disease, a dietary survey asking about food intake does not accurately reflect the actual levels of key immune-related nutrients in their blood, meaning the survey...
When people in a diet program start reporting their food intake more favorably to appear compliant, this distorts the results more than if everyone becomes slightly better or worse at reporting over...
When people change how they report their diet during an intervention, the statistical confidence intervals used to judge whether the diet worked often fail to include the true effect—sometimes...
If people in a diet intervention start reporting their food intake as better than it really is—perhaps to seem compliant—their reported improvements can be more than double the actual effect,...
If people in a diet intervention group become less consistent in how they report their food intake over time, researchers need about one-third more participants to detect a real effect; if everyone...
When people in a diet intervention study change how they report what they eat—either because they’re trying to please researchers or because they get better at estimating portions—this can make it...
This dietary questionnaire cannot reliably measure vitamin E or eicosapentaenoic acid (EPA) intake in older adults because the method used to validate it produced inconsistent results. This finding...
This dietary questionnaire moderately reflects actual β carotene levels in older adults, based on comparisons with blood tests and detailed food logs. This finding is from the abstract summary - full...
A dietary questionnaire designed for older adults accurately measures how much docosahexaenoic acid (DHA) people eat, based on comparisons with detailed food logs and blood tests. This finding is...
This questionnaire is not accurate at identifying people who eat more or less of alpha-linolenic acid, a plant-based omega-3 fat, because people’s reports don’t match their actual intake patterns.
When comparing what people reported eating to what was measured in their urine, sodium intake rankings were more accurate than what people reported in food diaries, suggesting urine tests are a...
This questionnaire is fairly accurate at identifying people who eat a lot or little of protein, selenium, caffeine, and folate, but it is not reliable for identifying those who eat a lot or little of...
When the same people filled out this food questionnaire twice, a year apart, their rankings for most nutrients stayed similar, meaning the tool gives consistent results over time.
This food questionnaire can tell whether someone eats more or less of a nutrient compared to others over time, but it cannot accurately measure exactly how much they eat.
A fatty acid called pentadecanoic acid, found in full-fat dairy, may help reverse some of the mitochondrial damage caused by too much linoleic acid by improving energy production and reducing signals...
High intake of linoleic acid may alter gut bacteria by reducing helpful anaerobic microbes and increasing harmful ones that trigger inflammation, which can weaken the gut lining and allow toxins into...