Browse evidence-based analysis of health-related claims and assertions
Working out your muscles might release helpful proteins, but this is just a theory from the abstract summary - full study details were not available
Having less body fat might help produce good hormones and reduce inflammation, but this is just a theory from the abstract summary - full study details were not available
When cells malfunction, it might cause problems like increased inflammation and aging processes, but this is just a theory from the abstract summary - full study details were not available
Exercise or certain drugs might help cells work better and make it easier to exercise, but this is just a theory from the abstract summary - full study details were not available
Liver transplant patients with fatty liver disease who took saroglitazar saw a small increase in belly fat and fat under the skin. This finding is from the abstract summary - full study details were not available
Taking saroglitazar didn't make the muscles weaker or more fatty in liver transplant patients with fatty liver disease. This finding is from the abstract summary - full study details were not available
When liver transplant patients with fatty liver disease had lower levels of a liver enzyme called alkaline phosphatase after treatment, their liver fat also tended to decrease more. This finding is from the abstract summary - full study details were not available
About half of all patients and over 60% of those with higher initial liver fat saw their liver fat drop by at least 30% after taking saroglitazar for 24 weeks. This finding is from the abstract summary - full study details were not available
For people who had a liver transplant and have fatty liver disease, taking saroglitazar for 24 weeks lowered the amount of fat in their liver from about 10% to 8% on average. This finding is from the abstract summary - full study details were not available
When oxygen was low, MOTS-c treated diabetic rat hearts used less ATP, which may help protect the heart during low-oxygen events like heart attacks.
MOTS-c treatment made the diabetic rats' heart cells have more mitochondria, which are the energy factories of cells.
Diabetic rats given MOTS-c had lower blood sugar levels after fasting, showing better control of glucose.
Diabetic rats had weaker heart mitochondria energy production, but MOTS-c treatment helped improve it back to normal levels.
When diabetic rats were given MOTS-c daily for three weeks, their heart walls became slightly thinner, which is a sign of less heart enlargement.
Apelin turns on genes that help build more mitochondria in muscles, improving energy production.
Apelin lowers blood fat levels and helps mice process sugar better, improving overall metabolic health.
Apelin's benefits for fat burning and mitochondria in muscles only work when AMPK is active, as shown in genetically modified mice.
Apelin activates a key energy-sensing enzyme in muscles, which helps reduce fat buildup and improve metabolism.
Apelin-treated mice burn more fat for energy during active periods compared to placebo-treated mice, shown by their breathing patterns.
Apelin reduces harmful fat byproducts in muscles, which helps muscles take up more glucose in response to insulin.
Apelin makes mouse muscles produce more mitochondria, the cell's energy factories, leading to better fat-burning capacity.
Apelin helps mouse muscles use oxygen more efficiently for energy production, especially when using fat as fuel.
Apelin-treated mice burn fat more completely in their muscles compared to placebo-treated mice, reducing harmful fat byproducts.
Giving apelin to obese, insulin-resistant mice for a month helps them lose body fat and lowers their blood sugar levels compared to mice given a placebo.