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Research Author

YUE YANG

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Studies by this author

1 study attributed to YUE YANG on the platform. Click a card to read the full analysis.

Study

Abstract A047: KRAS G12C and G12D mutants exhibit distinct conformational flexibility in the helix 3–switch 2 pocket that drives differential protein function

This study investigates why KRAS G12D and G12C oncogenic mutations differ in prevalence and function by analyzing their structural dynamics and effector binding preferences.