Do SGLT2 inhibitors improve insulin sensitivity in skeletal muscle of Zucker diabetic fatty rats by reducing triglycerides and increasing glucose uptake?

We analyzed one study on Zucker diabetic fatty rats and found that a 7-day course of an SGLT2 inhibitor was associated with improved insulin sensitivity in skeletal muscle. This improvement was linked to a reduction in triglycerides inside muscle cells and an increase in glucose uptake when insulin...