Do SGLT2 inhibitors reduce muscle and plasma triglycerides in diabetic rats without affecting liver triglycerides or body weight?

SGLT2 Inhibitors & Triglycerides1 min readUpdated May 31, 2026

What the Evidence Shows

We analyzed one study on diabetic rats and found that a 7-day course of an SGLT2 inhibitor lowered triglyceride levels in muscle tissue and plasma — the liquid part of blood — without changing triglyceride levels in the liver or the rats’ overall body weight [1]. This single observation suggests...

Update History

Published
May 31, 2026·Last updated May 31, 2026
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