Does a high-fat diet cause heart thickening and gene changes in macaque monkeys?

High-Fat Diet & Heart Changes1 min readUpdated June 6, 2026

What the Evidence Shows

We analyzed one study on macaque monkeys and found that a high-fat diet over 18 months was linked to heart muscle thickening in 46.43% of male monkeys aged 10 to 15 years, along with reduced activity in four genes tied to heart structure [1]. This is the only piece of evidence we’ve reviewed so...

Evidence from Studies

Supporting (0)
No supporting evidence found
Contradicting (0)
No contradicting evidence found
Primary Studies (1)

Chronic high‐fat diet induces multi‐organ dysfunction and metabolic homeostasis disruption in Macaca fascicularis

DOI: 10.1002/ame2.70124

Update History

Published
June 6, 2026·Last updated June 6, 2026
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