Does combination therapy with photodynamic therapy and anti-VEGF reduce the number of injections needed for polypoidal choroidal vasculopathy?

Photodynamic Therapy & Anti-VEGF1 min readUpdated June 17, 2026

What the Evidence Shows

We analyzed the available evidence on combination therapy for polypoidal choroidal vasculopathy and found that, so far, all reported assertions suggest that using photodynamic therapy along with anti-VEGF injections may lead to fewer anti-VEGF injections over time compared to anti-VEGF alone [1]....

Evidence from Studies

Supporting (0)
No supporting evidence found
Contradicting (0)
No contradicting evidence found
Primary Studies (1)

Comparative efficacy of photodynamic therapy (PDT), ranibizumab, aflibercept monotherapy, and combination therapies for polypoidal choroidal vasculopathy: a network meta-analysis of randomized controlled trials

DOI: 10.1186/s12886-025-04249-8

Update History

Published
June 17, 2026·Last updated June 17, 2026
  • Invalid DateNew topic created from assertion

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