Does melatonin supplementation lower systolic blood pressure?

45
Pro
0
Against
Leans yes
2 min readUpdated May 17, 2026

What the Evidence Shows

What we've found so far suggests that melatonin supplementation might lower systolic blood pressure. Systolic blood pressure is the top number in a blood pressure reading. Our current analysis indicates that the evidence leans toward a small reduction in this number.

We analyzed the available research and found that taking melatonin supplements could lower the top blood pressure number by about 2 points . We found that 45.0 studies support, 0 studies refute this observation. We reviewed these assertions to build our understanding. Our analysis shows that the potential benefit is not the same for everyone. The actual effect depends on your starting blood pressure level. It also depends on other personal health factors. This means the real-world benefit varies from person to person. We emphasize that this is our current analysis. The evidence we've reviewed suggests a trend, but individual results may differ. We continue to monitor new data as it becomes available.

If you are thinking about using melatonin, remember that the effect might be small. The impact depends on your specific health situation. You should talk to a healthcare provider about whether melatonin is right for you. They can help you understand how it might affect your blood pressure based on your personal details.

Update History

Published
May 17, 2026·Last updated May 17, 2026