How does radioactive iodine-131 destroy thyroid cells?
What the Evidence Shows
We analyzed the available evidence and found that radioactive iodine-131 destroys thyroid follicular cells by emitting ionizing radiation that damages their DNA and cellular structures [1]. This happens because the thyroid naturally absorbs iodine to make hormones, and when iodine-131 is taken in,...
Evidence from Studies
Disease status stratification individualizes radioiodine therapy for differentiated thyroid cancer: a prospective, multicenter, real-world study
DOI: 10.1186/s12885-026-16030-1
The effects of iodine 131 treatment on chromosomal and oxidative DNA damage in papillary thyroid carcinoma.
DOI: 10.1016/j.mrgentox.2024.503797
Thyroid Ablation with 1.1 GBq (30 mCi) Iodine-131 in Patients with Papillary Thyroid Carcinoma at Intermediate Risk for Recurrence
DOI: 10.1089/thy.2013.0479
Update History
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