Is combination photodynamic therapy and anti-VEGF therapy as safe as monotherapy for polypoidal choroidal vasculopathy?

Photodynamic Therapy Safety1 min readUpdated June 17, 2026

What the Evidence Shows

We analyzed the available evidence on combination therapy for polypoidal choroidal vasculopathy and found that combining photodynamic therapy with anti-VEGF drugs does not appear to increase eye complications compared to using either treatment alone [1]. Serious bleeding under the retina, a...

Evidence from Studies

Supporting (0)
No supporting evidence found
Contradicting (0)
No contradicting evidence found
Primary Studies (1)

Comparative efficacy of photodynamic therapy (PDT), ranibizumab, aflibercept monotherapy, and combination therapies for polypoidal choroidal vasculopathy: a network meta-analysis of randomized controlled trials

DOI: 10.1186/s12886-025-04249-8

Update History

Published
June 17, 2026·Last updated June 17, 2026
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