Is social isolation associated with C-reactive protein levels?

1 min readUpdated May 29, 2026

What the Evidence Shows

We analyzed the available evidence and found that people with few social contacts show variable links to C-reactive protein, a marker of inflammation in the body [1]. The evidence we’ve reviewed so far does not show a consistent pattern between low social contact and elevated C-reactive protein...

Evidence from Studies

Supporting (0)
No supporting evidence found
Contradicting (0)
No contradicting evidence found
Primary Studies (1)

The reciprocal associations between social deficits, social engagement, and inflammation: Longitudinal evidence comparing venous blood samples and dried blood spots and mapping the modifying role of phenotypic and genotypic depression.

DOI: 10.1016/j.bbi.2024.03.045

Update History

Published
May 29, 2026·Last updated May 29, 2026
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