What happens when IPMK is lost in intestinal epithelial cells in mice?

IPMK Loss in Gut Cells1 min readUpdated June 8, 2026

What the Evidence Shows

We analyzed the available evidence and found that when the IPMK gene is disabled in the gut lining cells of mice, it leads to lower levels of a molecule called InsP6, reduced activity of an enzyme named HDAC3, and changes in how genes are regulated. These changes appear to increase the production...

Evidence from Studies

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No supporting evidence found
Contradicting (0)
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Primary Studies (1)

Phytic acid (InsP6) activates HDAC3 epigenetic axis to maintain intestinal barrier function

DOI: 10.1038/s41467-026-68994-0

Update History

Published
June 8, 2026·Last updated June 8, 2026
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