What happens when the IPMK gene is deleted in intestinal cells?

IPMK Gene Deletion1 min readUpdated June 8, 2026

What the Evidence Shows

We analyzed the available evidence and found that removing the IPMK gene from intestinal cells in mice is linked to reduced HDAC3 activity, which appears to alter gene expression in a way that weakens the intestinal barrier [1]. HDAC3 is a protein involved in controlling how genes are turned on or...

Evidence from Studies

Supporting (0)
No supporting evidence found
Contradicting (0)
No contradicting evidence found
Primary Studies (1)

Phytic Acid (InsP6) Activates HDAC3 Epigenetic Axis to Maintain Intestinal Barrier Function

DOI: 10.1101/2024.09.15.613154

Update History

Published
June 8, 2026·Last updated June 8, 2026
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