Research Database

To examine the relationship between healthful and unhealthful low-fat dietary patterns and breast cancer risk in middle-aged women.

To evaluate whether dietary fructose induces hepatic insulin resistance through metabolic pathways independent of caloric excess or weight gain.

To assess the effect of chronic isoenergetic substitution of fructose for glucose or sucrose on fasting glycemic, insulinemic, and lipid markers in adults with...

To determine whether fructose and sucrose independently increase hepatic de novo lipogenesis without excessive caloric intake.

To assess dose-response associations between dietary macronutrient intake and risks of cardiovascular disease (CVD) morbidity/mortality and all-cause/cancer...

To determine whether replacing dietary carbohydrate with unsaturated fat or protein alters protein-based HDL subspecies linked to coronary heart disease (CHD)...

To determine whether carbohydrate or monounsaturated fat is a preferred replacement for saturated fat in individuals with metabolic risk abnormalities.

To assess the chronic effects of replacing saturated fat with refined carbohydrate or monounsaturated fat on insulin secretion and insulin sensitivity in...

To evaluate the evolving scientific understanding of dietary fats, sugars, whole grains, and fiber in relation to coronary heart disease (CHD) over 50 years.