Does Melatonin Help Heart Failure Patients Feel Better?
Melatonin as a Novel Drug to Improve Cardiac Function and Quality of Life in Heart Failure Patients: A Systematic Review and Meta‐Analysis
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Melatonin lowers cardiac stress markers (NT-proBNP) and fatigue without improving the heart's pumping capacity.
Most heart treatments aim directly at improving ejection fraction or pumping strength, but this shows physiological relief can happen independently.
Practical Takeaways
If you or a loved one has heart failure, discuss adding 3-20 mg of melatonin daily with a cardiologist to potentially reduce fatigue and improve daily well-being.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Melatonin lowers cardiac stress markers (NT-proBNP) and fatigue without improving the heart's pumping capacity.
Most heart treatments aim directly at improving ejection fraction or pumping strength, but this shows physiological relief can happen independently.
Practical Takeaways
If you or a loved one has heart failure, discuss adding 3-20 mg of melatonin daily with a cardiologist to potentially reduce fatigue and improve daily well-being.
Publication
Journal
Clinical Cardiology
Year
2025
Authors
Abolfazl Sam Daliri, Nima Goudarzi, A. Harati, Kourosh Kabir
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Claims (5)
Taking melatonin by mouth might lower a specific stress marker in the blood for people with a common type of heart failure. This suggests the supplement could help take the strain off the heart and calm stress hormones, even if it doesn't change how well the heart pumps.
Taking melatonin pills might help heart failure patients who are losing weight and feeling exhausted by boosting their appetite, cutting down their tiredness, and improving their overall nutrition.
Taking melatonin supplements every day for a couple of months might help people with heart failure feel better physically and mentally. Studies show that compared to a fake pill, those who took melatonin reported noticeably better quality of life scores.
Taking melatonin pills for heart failure patients doesn't seem to help their hearts pump blood better. Research shows that adding melatonin to their treatment doesn't make a meaningful difference in how well their hearts work compared to just taking a placebo.
Taking melatonin supplements helps improve blood vessel health in heart failure patients who don't have diabetes, but it doesn't seem to help those who do have diabetes. This suggests that a person's blood sugar levels might change how well melatonin works to protect the heart and blood vessels.