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The Study

Adult onset sucrase-isomaltase deficiency with secondary disaccharidase deficiency resulting from severe dietary carbohydrate restriction

In simple terms

This study looks at just one person who changed their diet and noticed a change in their body. It's like noticing you feel sick after eating a certain food, but it doesn't prove that food makes everyone sick.

20%

Analysis score

20/ 30

Maximum 30 for a case report.

Where the score came from

Reporting0
Methodology0
Publication100
Statistical0
Study type (basis of the score)
Case Report
Level 4 - Case series
What’s the bottom line?

This study examined what happens to digestive enzymes when adults drastically reduce carbohydrates from their diet.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Cross-Sectional & Case Series
Level 4
20

20 / 100

Quality score

Snapshots of a population at a single point in time, or descriptions of small groups. Can identify correlations and prevalence, but cannot determine cause and effect.

Cannot establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1This suggests that long-term extreme low-carb diets may reduce the gut's ability to produce certain digestive enzymes, potentially affecting sugar digestion.
  2. 2Severe carbohydrate restriction caused a secondary deficiency in intestinal brush-border enzymes.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Digestive Diseases and Sciences

Year

1983

Authors

B. Cooper, J. Scott, J. Hopkins, T. Peters

6 citations
Analysis v5
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.