The Study
Adult onset sucrase-isomaltase deficiency with secondary disaccharidase deficiency resulting from severe dietary carbohydrate restriction
This study looks at just one person who changed their diet and noticed a change in their body. It's like noticing you feel sick after eating a certain food, but it doesn't prove that food makes everyone sick.
Analysis score
Maximum 30 for a case report.
Where the score came from
This study examined what happens to digestive enzymes when adults drastically reduce carbohydrates from their diet.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 520 / 100
Quality score
Snapshots of a population at a single point in time, or descriptions of small groups. Can identify correlations and prevalence, but cannot determine cause and effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1This suggests that long-term extreme low-carb diets may reduce the gut's ability to produce certain digestive enzymes, potentially affecting sugar digestion.
- 2Severe carbohydrate restriction caused a secondary deficiency in intestinal brush-border enzymes.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Digestive Diseases and Sciences
Year
1983
Authors
B. Cooper, J. Scott, J. Hopkins, T. Peters
Related Content
Claims (4)
You don't actually need to eat carbohydrates to survive or keep your body running properly. Your body can make all the energy it needs from its own stored reserves and fat, so skipping carbs won't interfere with your basic biological functions.
Eating very few carbs for a long time might reduce the digestive enzymes in your gut, making it harder to break down food and potentially causing stomach issues and nutrient problems.
Following a very low-carb diet for a long time might cause your body to stop making enough of the enzymes needed to digest sugars properly. This can lead to stomach problems and might mean you need to change your diet or see a doctor to manage it.
Eating very few carbs for a long time might cause your small intestine to stop making enough digestive enzymes, because it adjusts to the lack of food it normally breaks down.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.