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The Study

The effect of sodium bicarbonate mini-tablets in a carbohydrate hydrogel on prolonged high-intensity cycling performance and metabolism in acute normobaric hypoxia

In simple terms

This study is like a fair test where cyclists took either a special pill or a fake pill without knowing which, then raced on a bike in thin air. The ones who took the real pill were a little faster, so we can say the pill probably helped — but only for these specific cyclists in this exact situation.

68%

Analysis score

68/ 90

Maximum 90 for a randomized controlled trial.

Where the score came from

Reporting40
Methodology77
Publication100
Statistical54
Study type (basis of the score)
Randomized Controlled Trial
Level 1b - Individual RCT
What’s the bottom line?

Cyclists at high altitudes get tired faster because their muscles get too acidic. This study gave them a special drink with baking soda that helps neutralize the acid.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Randomized Trials
Level 1b
68

68 / 100

Quality score

Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.

Can establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes — a 1.2% improvement in a 40 km race is meaningful for competitive cyclists, equivalent to gaining a small but race-winning edge.
  2. 2The cyclists who drank the baking soda drink finished their 40 km ride 1.2% faster (about 45 seconds) and had higher blood pH and bicarbonate levels, without feeling more tired or breathing harder.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

European Journal of Applied Physiology

Year

2026

Authors

Eli Spencer Shannon, S. Sparks, Lars R. McNaughton, Kelly Marrin, C. Bridge

Open Access
Analysis v6

Related Content

Claims (9)

Assertion

Sodium bicarbonate hydrogel improves athletic performance in low-oxygen conditions without changing how fast you pedal, your heart rate, or how much oxygen you use, meaning the improvement comes from better muscle function or energy efficiency, not from increased aerobic capacity.

Mechanistic
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Assertion

Taking sodium bicarbonate by mouth raises bicarbonate levels outside muscle cells, allowing hydrogen ions to leave the cells and lowering acid levels inside the cells.

Mechanistic
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Assertion

When trained male cyclists consume sodium bicarbonate mixed in a carbohydrate gel during intense exercise in low-oxygen conditions, they experience the same level of stomach discomfort as when they consume sodium bicarbonate in traditional forms.

Descriptive
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Assertion

Taking sodium bicarbonate with a carbohydrate gel during intense cycling in low-oxygen conditions increases the balance of charged ions outside muscle cells, which directly improves muscle electrical activity and decreases fatigue.

Mechanistic
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Assertion

Trained male cyclists who consume 0.3 grams of sodium bicarbonate per kilogram of body weight in a carbohydrate gel 90 minutes before cycling 40 kilometers under simulated high-altitude conditions complete the ride 1.2% faster because the sodium bicarbonate reduces the buildup of acid in their blood during intense effort.

Causal
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Assertion

When trained male cyclists consume sodium bicarbonate mixed with a carbohydrate gel at a dose of 0.3 grams per kilogram of body weight before exercising in low-oxygen conditions, their blood bicarbonate levels rise by 4.8 mmol/L and their blood pH increases, confirming systemic alkalosis without lowering oxygen levels.

Quantitative
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Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.