The Study
The effects of incidental findings from whole-body MRI on the frequency of biopsies and detected malignancies or benign conditions in a general population cohort study
This study found that when people got told about weird bumps or lab results from a big body scan, they ended up getting more biopsies afterward. But we can’t say the scan caused the biopsies — maybe those people were already more worried about their health or went to the doctor more often.
Analysis score
Maximum 72 for a cohort study.
Where the score came from
When people got full-body MRI scans in a study, doctors told them about weird spots they found—even if those spots were probably harmless. This made people get more biopsies, but most of those biopsies didn’t find cancer.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 559 / 100
Quality score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Yes—most people who got scans ended up with painful, costly, and unnecessary procedures that didn’t help them live longer or healthier.
- 2After scans, biopsies went up by 44% (from 6.9 to 9.9 per 100 people per year).
- 3MRI disclosures caused 2.3x more biopsies.
- 487% more biopsies found nothing cancerous.
- 5Only 3.8x more cancers were found—but still very few overall.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
European Journal of Epidemiology
Year
2020
Authors
Adrian Richter, Elizabeth Sierocinski, Stephan Singer, Robin Bülow, Carolin Hackmann, Jean-François Chenot, Carsten Oliver Schmidt
Related Content
Claims (6)
Getting a full-body MRI scan to check for problems isn't worth the cost because it often finds harmless things that cause stress and tests, and no one has proven it helps people live longer.
When people who’ve had cancer before are told about unexpected health findings from a research study, they’re almost three times more likely to get a biopsy — suggesting that sharing these findings might lead to more testing in people already at higher risk.
When people are told about unexpected findings from a full-body MRI scan, they’re much more likely to get unnecessary biopsies that turn out to be harmless — meaning doctors might be doing too many tests that don’t find cancer.
When doctors tell patients about unexpected findings on a full-body MRI scan, it leads to over three times more biopsies that find cancer—but even then, very few actual cancers are found, so it might not be worth the hassle and cost.
When people get full-body scans or lab tests and are told about unexpected results—even if those results might not mean anything—they end up getting more biopsies, especially when the scan findings are shared. This might lead to too many medical tests that aren’t really needed.
When doctors tell patients about unexpected lab results, it leads to 37% more biopsies—but even more biopsies happen when doctors share unexpected MRI results, meaning imaging scans seem to trigger more follow-up tests than blood tests.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.