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The Study

Creatine Supplementation Prior to Strength Exercise Training Is Not Superior in Preventing Muscle Mass Loss Compared with Standard Nutritional Recommendations in Females After Bariatric Surgery: A Pilot Study

In simple terms

This study gave some women creatine and others a fake pill, then saw if creatine helped them keep muscle after weight-loss surgery. It found no big difference, but because so few women were in the study, we can't be super sure creatine doesn't help at all — it just didn't help noticeably here.

46%

Analysis score

46/ 90

Maximum 90 for a randomized controlled trial.

Where the score came from

Reporting0
Methodology58
Publication100
Statistical23
Study type (basis of the score)
Randomized Controlled Trial
Level 1b - Individual RCT
What’s the bottom line?

Women who had weight-loss surgery did strength training and took either creatine or a sugar pill to see if creatine helped keep their muscles.

Where does this study sit?

Systematic Reviews & Meta-analyses

Max 100

Randomized Trials

Max 90

Cohort Studies

Max 72

Case-Control

Max 58

Cross-Sectional

Max 44

Case Reports & Series

Max 30

Expert Opinion

Max 5
StrongerWeaker
Randomized Trials
Level 1b
46

46 / 100

Quality score

Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.

Can establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1No, the muscle loss was small and similar in both groups — creatine didn't make a meaningful difference in this context.
  2. 2Both groups lost about 9.5 kg of weight and 0.6–0.7 kg of muscle.
  3. 3Creatine didn't help keep more muscle than the sugar pill.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Obesity Surgery

Year

2024

Authors

Marcelo Diaz-Pizarro, Johanna Pino-Zúñiga, Mariela Olivares Gálvez, Carolina Rendon Vesga, Rafael Luengas Tello, Juan Camilo Duque Seguro, Jorge Cancino-López

4 citations
Analysis v4
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.