Are toxic chemicals in non-stick pans linked to cancer?

Original Title

Perfluoroalkyl and polyfluoroalkyl substances and Cancer risk: results from a dose-response Meta-analysis

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Summary

Scientists looked at many studies to see if chemicals called PFAS — found in non-stick pans, waterproof clothes, and some foods — might make people more likely to get cancer.

Proposed Mechanism
PFDA-induced disruption of gap junctional intercellular communication (GJIC)
Suggested
PFDA-mediated inhibition of UDP-glucuronosyltransferase (UGT) enzymes
Suggested
PFDA-induced oxidative stress and impaired apoptosis
Suggested
PFDA-mediated activation of NLRP3 inflammasome and chronic inflammation
Suggested
PFOA/PFOS-induced epigenetic alterations and DNA methylation changes
Suggested
PFDA-induced disruption of oocyte maturation via calcium and GJIC dysregulation
Suggested

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Quality Analysis
Methodology
60%
Moderate QualityOverall Score
Systematic Review With Meta-AnalysisMedicine

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