More Sets Help You Get Stronger, But Not Always Bigger

Original Title

The Resistance Training Dose Response: Meta-Regressions Exploring the Effects of Weekly Volume and Frequency on Muscle Hypertrophy and Strength Gains.

Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms

Summary

Doing more weightlifting sets makes you stronger and bigger, but after a point, extra sets give less benefit—especially for strength. Doing workouts more often helps strength more than muscle size.

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Surprising Findings

Training frequency has no consistent effect on muscle growth—only on strength.

Most fitness influencers claim 'train each muscle 2–3x/week for max growth,' but this meta-analysis shows frequency doesn’t reliably increase hypertrophy when volume is fixed.

Practical Takeaways

For strength: Increase training frequency (e.g., 3–4x/week per muscle) before adding more sets. For hypertrophy: Focus on 10–15 direct sets per muscle per week, then stop adding volume.

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48%
Moderate QualityOverall Score

Publication

Journal

Sports medicine

Year

2025

Authors

Joshua C. Pelland, Jacob F. Remmert, Zac P Robinson, Seth R. Hinson, Michael C. Zourdos

8 citations
Analysis v1