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The Study

The plasma membrane potential of human neutrophils. Role of ion channels and the sodium/potassium pump.

In simple terms

This study looked at how tiny electric signals change in white blood cells when scientists tweak the chemicals around them. It shows what happens when you turn certain switches on or off, but it doesn't prove those switches cause real-life changes in your body.

27%

Analysis score

27/ 44

Maximum 44 for a cross-sectional study.

Where the score came from

Reporting0
Methodology19
Publication100
Statistical0
Study type (basis of the score)
Cross-Sectional Study
Level 4 - Case series
What’s the bottom line?

White blood cells have an electric charge inside them, like a tiny battery. This charge helps them work properly.

Where does this study sit?

Systematic Reviews & Meta-analyses

Max 100

Randomized Trials

Max 90

Cohort Studies

Max 72

Case-Control

Max 58

Cross-Sectional

Max 44

Case Reports & Series

Max 30

Expert Opinion

Max 5
StrongerWeaker
Case Reports & Series
Level 4
27

27 / 100

Quality score

Detailed descriptions of individual patients or small groups. Valuable for identifying new conditions or side effects, but cannot establish generalizable conclusions.

Cannot establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes — this means potassium channels are more important than the pump for keeping the cell ready to fight infection.
  2. 2When calcium is removed, the charge drops.
  3. 3When calcium is added back, the charge returns.
  4. 4The charge is mostly kept by potassium leaking out, not by a pump.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Biochimica et biophysica acta

Year

1989

Authors

A. Majander, M. Wikström

16 citations
Analysis v4
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.