What happens to muscles when mice with big muscles eat less?
The effect of caloric restriction on the forelimb skeletal muscle fibers of the hypertrophic myostatin null mice.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Fast-twitch fibers atrophied more than other fiber types during caloric restriction
Myostatin-null mice have exaggerated muscle growth, so researchers might expect them to resist atrophy—but instead, their most powerful fibers were most sensitive to calorie loss.
Practical Takeaways
If you're dieting and want to preserve strength, prioritize protein and resistance training—especially for explosive movements.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Fast-twitch fibers atrophied more than other fiber types during caloric restriction
Myostatin-null mice have exaggerated muscle growth, so researchers might expect them to resist atrophy—but instead, their most powerful fibers were most sensitive to calorie loss.
Practical Takeaways
If you're dieting and want to preserve strength, prioritize protein and resistance training—especially for explosive movements.
Publication
Journal
Acta histochemica
Year
2017
Authors
M. Elashry, A. Matsakas, S. Wenisch, S. Arnhold, K. Patel