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The Study

Resistance training increases myofibrillar protein synthesis in middle-to-older aged adults consuming a typical diet with no influence of protein source: a randomized controlled trial

In simple terms

This study showed that lifting weights for 10 days made muscles in older adults make more protein, no matter if they ate chicken or peas for protein. But it didn't show if their muscles got bigger or stronger — just that the protein-making machine was working a bit faster.

72%

Analysis score

72/ 90

Maximum 90 for a randomized controlled trial.

Where the score came from

Reporting40
Methodology71
Publication100
Statistical77
Study type (basis of the score)
Randomized Controlled Trial
Level 1b - Individual RCT
What’s the bottom line?

Scientists gave older adults either whey (from milk) or pea protein for 10 days while they did leg workouts every other day to see if one made muscles grow better.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Randomized Trials
Level 1b
72

72 / 100

Quality score

Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.

Can establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes — workouts help muscles rebuild daily, and plant protein may help heart health without hurting muscle growth.
  2. 2Muscle protein synthesis went up by about 11–12% with workouts, no matter if they ate whey or pea protein.
  3. 3Plant protein also lowered bad cholesterol by 13%.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

The American Journal of Clinical Nutrition

Year

2025

Authors

Marie Korzepa, J. Quinlan, Ryan N. Marshall, Lucy M. Rogers, Archie E. Belfield, Yasir S. Elhassan, A. Lawson, C. Ayre, J. Senden, J. Goessens, Elisa I. Glover, G. Wallis, Luc J. C. van Loon, Leigh Breen

Open Access
3 citations
Analysis v5

Related Content

Claims (6)

Assertion

For adults aged 50 to 70 who consume 1.0 gram of protein per kilogram of body weight daily, myofibrillar protein synthesis rates are the same whether the protein comes from whey or pea, during both resistance training and rest over 10 days.

Descriptive
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Assertion

In adults aged 50–70, 10 days of resistance training increases myofibrillar protein synthesis but does not lead to measurable improvements in muscle strength, muscle structure, or nerve signaling to muscles.

Descriptive
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Assertion

In adults aged 50 to 70, performing resistance training every other day for 10 days increases the rate of muscle protein synthesis by 11-12%, whether their daily protein comes from animal or plant sources.

Causal
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Assertion

In adults aged 50–70, consuming 1.0 gram of plant-based protein per kilogram of body weight for 10 days lowers non-HDL cholesterol by about 13% without changing other blood lipids, kidney function, or nitrogen balance.

Quantitative
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Assertion

For adults aged 50 to 70, consuming 1.0 gram of protein per kilogram of body weight each day, spread across meals and sourced from either whey or pea protein, maintains nitrogen balance over 10 days without change, regardless of the protein type.

Descriptive
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Assertion

Resistance-trained adults who consume 0.7 to 1.0 grams of protein per pound of body weight each day maintain and build muscle.

Quantitative
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Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.