Does eating more fat make you less full when your body releases a fullness hormone?

Original Title

Effects of nutritional supplementation on the appetite and energy intake responses to IV cholecystokinin in older adults.

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Summary

Scientists gave older adults lots of fatty food for two weeks, then injected them with a hormone that makes you feel full. They then let them eat as much as they wanted.

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Proposed Mechanism
CCK-8 suppresses appetite and energy intake via satiety signaling
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Quality Analysis
Methodology
58%
Moderate QualityOverall Score
Randomized Controlled TrialMedicine/Nutrition

Systematic Reviews & Meta-Analyses

Max 100

Randomized Controlled Trials

Max 90

Cohort Studies

Max 72

Case-Control Studies

Max 58

Cross-Sectional Studies

Max 44

Case Reports & Case Series

Max 30

Expert Opinion & Narrative Reviews

Max 5
StrongerWeaker
Randomized Controlled Trials
Level 1b
58

58 / 90

Evidence Score

Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.

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