Do PCSK9 medicines help lower bad cholesterol?
Ldl-cholesterol reduction with PCSK9 inhibitors: A meta-analysis of randomised controlled trials.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
PCSK9 inhibitors achieve up to 81% reduction in LDL-C even in patients already on statins.
Most additional cholesterol drugs only offer modest improvements after statins, so an 81% drop is unusually large and could change treatment expectations.
Practical Takeaways
Talk to your doctor about PCSK9 inhibitors if your LDL cholesterol remains high despite taking statins or other lipid-lowering drugs.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
PCSK9 inhibitors achieve up to 81% reduction in LDL-C even in patients already on statins.
Most additional cholesterol drugs only offer modest improvements after statins, so an 81% drop is unusually large and could change treatment expectations.
Practical Takeaways
Talk to your doctor about PCSK9 inhibitors if your LDL cholesterol remains high despite taking statins or other lipid-lowering drugs.
Publication
Journal
Atherosclerosis
Year
2017
Authors
M. Casula, L. Scotti, O. Bernocchi, F. Galimberti, E. Tragni, G. Corrao, A. Catapano
Related Content
Claims (4)
Adding PCSK9 drugs to cholesterol-lowering statins can slash bad cholesterol by as much as 81% in people with high cholesterol.
These cholesterol drugs, called PCSK9 inhibitors, probably help lower bad cholesterol in many types of patients — more than fake pills or other cholesterol medicines.
PCSK9 inhibitors can help lower bad cholesterol, either when added to other treatments or used instead of them.
These cholesterol drugs work well for lots of different people, even if they're already taking other meds for high cholesterol.