Vinegar chemical helps sugar control in diabetic mice
Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Mice with diabetes had lower blood sugar after drinking water with a little vinegar chemical (acetic acid) for 8 weeks. Their livers also changed how they make sugar, and a key energy sensor (AMPK) turned on in liver cells.
Surprising Findings
A common kitchen ingredient may activate the same pathway as diabetes drugs.
Most people think of vinegar as a condiment, not a metabolic modulator. The fact that it may activate AMPK — a target of prescription medications — is unexpected and intriguing.
Practical Takeaways
Some people with prediabetes or type 2 diabetes might consider discussing vinegar consumption with their doctor as a complementary strategy.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Mice with diabetes had lower blood sugar after drinking water with a little vinegar chemical (acetic acid) for 8 weeks. Their livers also changed how they make sugar, and a key energy sensor (AMPK) turned on in liver cells.
Surprising Findings
A common kitchen ingredient may activate the same pathway as diabetes drugs.
Most people think of vinegar as a condiment, not a metabolic modulator. The fact that it may activate AMPK — a target of prescription medications — is unexpected and intriguing.
Practical Takeaways
Some people with prediabetes or type 2 diabetes might consider discussing vinegar consumption with their doctor as a complementary strategy.
Publication
Journal
Biochemical and biophysical research communications
Year
2006
Authors
S. Sakakibara, T. Yamauchi, Y. Oshima, Y. Tsukamoto, T. Kadowaki
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Claims (7)
Acetic acid turns on a key energy sensor in liver cells, which tells the body to start using stored energy.
If you regularly consume something like vinegar (which has acetic acid), it might help your body switch to burning fat faster when you're not eating carbs or during fasting.
Mice with a condition like type 2 diabetes had lower blood sugar after drinking water with a little vinegar (acetic acid) for two months. This suggests vinegar might help control blood sugar in diabetes.
Acetic acid might help lower blood sugar in diabetic mice by turning on a key energy-sensing protein in the liver, based on lab tests and gene activity clues.
In rat liver cells, a substance related to vinegar (sodium acetate) turns on a key energy sensor and lowers the activity of genes involved in sugar and fat production, which might explain how vinegar helps with metabolism.