Vinegar chemical helps sugar control in diabetic mice
Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Mice with diabetes had lower blood sugar after drinking water with a little vinegar chemical (acetic acid) for 8 weeks. Their livers also changed how they make sugar, and a key energy sensor (AMPK) turned on in liver cells.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
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Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Mice with diabetes had lower blood sugar after drinking water with a little vinegar chemical (acetic acid) for 8 weeks. Their livers also changed how they make sugar, and a key energy sensor (AMPK) turned on in liver cells.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 59 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Sakakibara S, Yamauchi T, Oshima Y, Tsukamoto Y, Kadowaki T
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Acetic acid turns on a key energy sensor in liver cells, which tells the body to start using stored energy.
If you regularly consume something like vinegar (which has acetic acid), it might help your body switch to burning fat faster when you're not eating carbs or during fasting.
Mice with a condition like type 2 diabetes had lower blood sugar after drinking water with a little vinegar (acetic acid) for two months. This suggests vinegar might help control blood sugar in diabetes.
Acetic acid might help lower blood sugar in diabetic mice by turning on a key energy-sensing protein in the liver, based on lab tests and gene activity clues.
In rat liver cells, a substance related to vinegar (sodium acetate) turns on a key energy sensor and lowers the activity of genes involved in sugar and fat production, which might explain how vinegar helps with metabolism.