Shingles Shot Might Help Keep Your Brain Younger
The effect of shingles vaccination at different stages of the dementia disease course
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Publication
Journal
Cell
Year
2025
Authors
M. Xie, Markus Eyting, Christian Bommer, H. Ahmed, Pascal Geldsetzer
Related Content
Claims (8)
If kids born just before and after a vaccine eligibility cutoff get vaccinated at different times, scientists can compare them to see if getting the vaccine early helps prevent dementia later in life — like a real-life experiment without random assignment.
People who got the shingles vaccine didn’t have more or fewer other health problems than those just barely eligible for it—and since those groups were otherwise similar, it looks like the vaccine might help lower dementia risk, not just luck or other health habits.
If you can stop the chickenpox virus from waking up again in your nerves, it might calm down brain swelling and reduce harmful protein buildups that lead to memory problems and dementia.
People with dementia who got the shingles vaccine were nearly 30% less likely to die from dementia over nine years—maybe the vaccine helps slow down how fast dementia gets worse, even in advanced stages.
Getting the shingles vaccine might help older adults (79–80 years old) stay mentally sharper longer—studies show they were 3.1% less likely to be diagnosed with mild memory problems over nine years.