Too Much Exercise Can Stress Your Body’s Defenses
Oxidative stress biomarkers responses to physical overtraining: implications for diagnosis.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
When strong guys lift too much weight for too long, their bodies show signs of stress and weakened defenses. Scientists checked their blood and pee to see how bad it got.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
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Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
When strong guys lift too much weight for too long, their bodies show signs of stress and weakened defenses. Scientists checked their blood and pee to see how bad it got.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 525 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Margonis K, Fatouros IG, Jamurtas AZ, Nikolaidis MG, Douroudos I, Chatzinikolaou A, Mitrakou A, Mastorakos G, Papassotiriou I, Taxildaris K, Kouretas D
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Claims (3)
When guys who lift weights train too much, their body's natural antioxidants take a hit — they lose a lot of the good kind and build up more of the used-up kind, which might be why they start performing worse.
If guys who lift weights train too much — like a whole lot in a week — their bodies might get stressed in a way that could hurt their performance, and scientists can see this stress through certain markers in their body.
In guys who lift weights a lot, certain chemicals in their urine that show stress on the body are closely linked to both worse performance and more training — meaning they might help tell when someone’s overdoing it.