The Claim
In male resistance-trained individuals, overtraining is associated with a 31% decrease in reduced glutathione (GSH), a 56% decline in the GSH/GSSG ratio, and a 25% increase in oxidized glutathione (GSSG), indicating impaired antioxidant defense capacity, which may contribute to performance deterioration during excessive training.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When guys who lift weights train too much, their body's natural antioxidants take a hit — they lose a lot of the good kind and build up more of the used-up kind, which might be why they start performing worse.
See the scientific wording
In male resistance-trained individuals, overtraining is associated with a 31% decrease in reduced glutathione (GSH), a 56% decline in GSH/GSSG ratio, and a 25% increase in oxidized glutathione (GSSG), indicating impaired antioxidant defense capacity, which may contribute to performance deterioration during excessive training.
What the research says
1 studyStudy: Oxidative stress biomarkers responses to physical overtraining: implications for diagnosis.
The study looked at male weightlifters who trained too hard and found their antioxidant levels dropped and oxidized stress increased, just as the claim says, which helps explain why they performed worse.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.