When guys who lift weights train too much, their body's natural antioxidants take a hit — they lose a lot of the good kind and build up more of the used-up kind, which might be why they start performing worse.

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Pro

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Against

Evidence from Studies

Supporting (1)

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Community contributions welcome

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Oxidative stress biomarkers responses to physical overtraining: implications for diagnosis.

Cross-Sectional Study

Human

2007 Sep 15

The study looked at male weightlifters who trained too hard and found their antioxidant levels dropped and oxidized stress increased, just as the claim says, which helps explain why they performed worse.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oxidative stress biomarkers responses to physical overtraining: implications for diagnosis.

Score: 25

DOI: 10.1016/j.freeradbiomed.2007.05.022

Similar Assertions

In guys who lift weights a lot, certain chemicals in their urine that show stress on the body are closely linked to both worse performance and more training — meaning they might help tell when someone’s overdoing it.

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