Does adding ezetimibe to statins help high-risk heart patients?
Impact of Lipid-Lowering Combination Therapy With Statins and Ezetimibe vs Statin Monotherapy on the Reduction of Cardiovascular Outcomes: A Meta-analysis.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Some heart patients need extra help to lower bad cholesterol. This study looked at whether adding a drug called ezetimibe to statins works better than just using statins alone.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
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Max 72Case-Control Studies
Max 58Cross-Sectional Studies
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Evidence Score
The highest quality evidence. These studies systematically search, appraise, and synthesize results from multiple individual studies, providing the most reliable summary of current knowledge.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Some heart patients need extra help to lower bad cholesterol. This study looked at whether adding a drug called ezetimibe to statins works better than just using statins alone.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 539 / 100
Evidence Score
The highest quality evidence. These studies systematically search, appraise, and synthesize results from multiple individual studies, providing the most reliable summary of current knowledge.
Publication
Authors
Banach M, Jaiswal V, Ang SP, Sawhney A, Deb N, Amarenco P, Gaita D, Reiner Z, Pećin I, Lavie CJ, Penson PE, Toth PP, Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group and the International Lipid Expert Panel (ILEP)
Related Content
Claims (7)
Ezetimibe helps lower bad cholesterol by stopping your gut from absorbing it, and even though it works well and doesn't cost much, doctors don't use it as much as they could.
For people at very high risk of heart problems, taking both a statin and ezetimibe might help them live longer than taking just a statin alone.
For people at very high risk of heart problems, taking a cholesterol drug (statin) with another drug (ezetimibe) is just as safe and easy to stick with as taking the statin alone.
For people at very high risk of heart problems, taking a cholesterol drug called ezetimibe along with a statin might lower their chances of serious heart issues more than taking just a statin alone.
Taking both a statin and ezetimibe together may help prevent strokes better than taking just a statin, especially in people at very high risk.