Can a special magnesium pill help you sleep better and feel more awake?

Original Title

Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial

Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms

Summary

This study tested a special kind of magnesium called MgT that can reach the brain. People took it for 3 weeks to see if it helped them sleep deeper and feel more energetic during the day.

Proposed Mechanism
Magnesium-L-threonate enhances neuronal magnesium levels to improve mitochondrial function and ATP production
Supported by evidence
Magnesium-L-threonate modulates GABAergic neurotransmission to promote neural inhibition and sleep onset
Supported by evidence
Magnesium-L-threonate supports melatonin synthesis via N-acetyltransferase activation
Suggested

Unlock Full Mechanism Details

Sign up free to explore the biological pathways and causal mechanisms.

Quality Analysis
Methodology
61%
Moderate QualityOverall Score
Randomized Controlled TrialMedicine

Systematic Reviews & Meta-Analyses

Max 100

Randomized Controlled Trials

Max 90

Cohort Studies

Max 72

Case-Control Studies

Max 58

Cross-Sectional Studies

Max 44

Case Reports & Case Series

Max 30

Expert Opinion & Narrative Reviews

Max 5
StrongerWeaker
Randomized Controlled Trials
Level 1b
61

61 / 90

Evidence Score

Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.

Sign up free to unlock the full quality breakdown with evidence strength scoring, statistical analysis, and detailed methodology.