Does blocking one hormone stop testicles from making testosterone?
Plasma testosterone response to short-term human chorionic gonadotropin administration in men with follicle-stimulating hormone suppressed by exogenous estrogen.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
FSH suppression had no effect on testosterone response to HCG
For decades, FSH has been assumed to play a supportive role in Leydig cell function — this study directly challenges that by showing testosterone production remains unchanged without it.
Practical Takeaways
Men on HCG therapy for low testosterone may not need FSH-boosting treatments for immediate testosterone output.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
FSH suppression had no effect on testosterone response to HCG
For decades, FSH has been assumed to play a supportive role in Leydig cell function — this study directly challenges that by showing testosterone production remains unchanged without it.
Practical Takeaways
Men on HCG therapy for low testosterone may not need FSH-boosting treatments for immediate testosterone output.