The Study
Polyendocrine metabolic ovarian syndrome in pregnancy: pathophysiology and outcomes.
This article is like a story that pulls together other people's research about a health condition, but it doesn't do any new experiments or check how good those other studies were. So it can tell you what people think might be linked, but it can't prove that one thing causes another.
Analysis score
Maximum 5 for a narrative review.
Where the score came from
Some women have a condition called PMOS that makes their bodies handle sugar and hormones differently, which can cause problems during pregnancy.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 51 / 100
Quality score
Systematic reviews and meta-analyses of cohort studies. They sit above a single cohort study but below a single randomized trial, because the underlying evidence is still observational.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Yes — these complications can be serious for both mom and baby, and extra monitoring can help prevent them.
- 21 in 8 pregnant women have PMOS; they are more likely to get gestational diabetes, high blood pressure, preterm birth, or have babies with low weight.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Nature reviews. Endocrinology
Year
2026
Authors
H. Teede, E. Vanky, T. Piltonen, E. Stener-Victorin, L. Moran, Mahnaz Bahri Khomami
Related Content
Claims (6)
Polyendocrine metabolic ovarian syndrome increases the risk of complications during pregnancy, but current prenatal care guidelines and medical practice do not consistently identify it as a distinct risk factor.
Women with polyendocrine metabolic ovarian syndrome who are overweight or obese before pregnancy and gain too much weight during pregnancy have a higher risk of complications during pregnancy.
Women with polyendocrine metabolic ovarian syndrome have higher rates of gestational diabetes, high blood pressure during pregnancy, preterm birth, restricted fetal growth, and low birth weight, due to elevated insulin levels, high androgen levels, and common pre-pregnancy obesity.
Guidelines from 2023 state that pregnant individuals with polyendocrine metabolic ovarian syndrome should be identified as higher-risk to enhance detection, prevention, and treatment of related health issues.
Women with polyendocrine metabolic ovarian syndrome experience higher rates of metabolic and vascular complications during pregnancy due to the interaction between their condition and normal pregnancy changes.
In patients with PMOS, weight gain occurs as a result of metabolic dysfunction.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.