Can eating less slow down aging?
Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Caloric restriction slowed aging on DunedinPACE but not on PhenoAge or GrimAge—despite all being DNA methylation clocks.
Most people assume all 'biological age' tests are interchangeable. This shows they’re not—some detect lifestyle changes, others don’t.
Practical Takeaways
Try reducing your daily calorie intake by 15–20% for long-term health and potential aging benefits.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Caloric restriction slowed aging on DunedinPACE but not on PhenoAge or GrimAge—despite all being DNA methylation clocks.
Most people assume all 'biological age' tests are interchangeable. This shows they’re not—some detect lifestyle changes, others don’t.
Practical Takeaways
Try reducing your daily calorie intake by 15–20% for long-term health and potential aging benefits.
Publication
Journal
Nature Aging
Year
2023
Authors
R. Waziry, C. Ryan, D. Corcoran, K. Huffman, M. Kobor, M. Kothari, G. Graf, V. Kraus, W. Kraus, D. Lin, C. Pieper, M. Ramaker, M. Bhapkar, S. Das, L. Ferrucci, W. J. Hastings, M. Kebbe, D. Parker, S. Racette, I. Shalev, B. Schilling, D. Belsky
Related Content
Claims (6)
A new aging test called DunedinPACE can spot small changes from healthy habits better than older tests, especially after just a couple of years of eating less — making it a better tool for testing anti-aging treatments quickly.
Cutting calories a bit for two years might slow how fast your body ages on a cellular level, according to a study on healthy adults who aren’t overweight.
Cutting calories for two years doesn’t seem to change certain biological age clocks in healthy adults, even though other signs of aging improved.
Cutting calories helps people get healthier, and while a DNA aging test called DunedinPACE shows some of these benefits, it only catches a small part of the full picture.
If healthy adults eat 20% less food, it might slow down how fast their body ages — and the more they cut calories, the more it slows, according to one study.