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Why your muscles don't hurt as much the second time you lift weights
Original Title
The repeated bout effect and heat shock proteins: intramuscular HSP27 and HSP70 expression following two bouts of eccentric exercise in humans.
doi:10.1046/J.1365-201X.2002.00922.X31%
Lower Quality
Methodology score · 31/100
Cohort Human
Fit Body Science breakdown
We translate health research into clear, actionable insights. Here’s what this study found and what it means for you.
Not medical advice. For informational purposes only. Always consult a healthcare professional.
What’s the bottom line?
When you do a tough workout that hurts your muscles, the next time you do the same workout a month later, your muscles don't hurt as much. But your body doesn't make more of the stress proteins (HSPs) the second time — instead, it starts with less of them already in the muscle.
Score breakdown, methodology, COI, evidence analysis & raw study data
Publication
Authors
Thompson HS, Clarkson PM, Scordilis SP