Does a weight-loss shot also help protect the heart?
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A special medicine called semaglutide, given as a weekly shot, was tested to see if it helps prevent heart attacks, strokes, or heart-related deaths in people with heart disease and extra weight—but no diabetes.
Surprising Findings
A weight-loss drug significantly reduces heart events in non-diabetic patients with heart disease.
Previously, GLP-1 drugs were known to help diabetics’ hearts—but this proves the benefit extends to non-diabetics with obesity, a major shift in understanding.
Practical Takeaways
If you have heart disease and obesity but not diabetes, talk to your doctor about whether semaglutide could reduce your heart risk.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A special medicine called semaglutide, given as a weekly shot, was tested to see if it helps prevent heart attacks, strokes, or heart-related deaths in people with heart disease and extra weight—but no diabetes.
Surprising Findings
A weight-loss drug significantly reduces heart events in non-diabetic patients with heart disease.
Previously, GLP-1 drugs were known to help diabetics’ hearts—but this proves the benefit extends to non-diabetics with obesity, a major shift in understanding.
Practical Takeaways
If you have heart disease and obesity but not diabetes, talk to your doctor about whether semaglutide could reduce your heart risk.
Publication
Journal
The New England journal of medicine
Year
2023
Authors
A. M. Lincoff, K. Brown-Frandsen, H. Colhoun, J. Deanfield, S. Emerson, Sille Esbjerg, S. Hardt-Lindberg, G. Hovingh, S. Kahn, Robert F. Kushner, I. Lingvay, Tugce K Oral, Marie M Michelsen, Jorge Plutzky, C. W. Tornøe, D. Ryan
Related Content
Claims (3)
If you're obese and have heart disease but not diabetes, taking semaglutide might lower your chances of having a serious heart problem by 20%.
A weekly injection of semaglutide (2.4 mg) helps lower the risk of serious heart problems like heart attack, stroke, or heart-related death by 20% in people over 45 who have heart disease and are overweight, but don’t have diabetes, compared to a fake treatment.
For adults with heart disease and obesity who don’t have diabetes, taking a weekly semaglutide shot (2.4 mg) leads to more than twice as many people stopping treatment because of side effects compared to those taking a dummy shot.