Can mice absorb tiny HA pills through their tummy?
Steady state plasma and tissue distribution of low molecular weight hyaluronic acid after oral administration in mice
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave mice tiny HA pills and checked if the HA showed up in their blood and body parts.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 510 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave mice tiny HA pills and checked if the HA showed up in their blood and body parts.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 510 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Publication
Authors
Mannino F, Irrera N, Pallio G, Bitto A
Related Content
Claims (4)
If you give female mice a special kind of hyaluronic acid pill every day for a week, their bodies end up with more of this substance in their blood and several organs like their skin, eyes, and bladder.
If you give tiny mice a special kind of jelly-like substance through their mouth for a week, it shows up in places like their eyes and bladder—even though they didn’t swallow it there—meaning it traveled through their body.
Giving mice a specific type of hyaluronic acid pill every day for a week doesn't make more of it show up in their blood or body tissues compared to mice that just got water.
When you swallow hyaluronic acid, only about 2% of it actually gets into your bloodstream, no matter how big or small the molecules are, because your gut breaks it down too much and doesn’t let much through.