How lifting weights helps older men with and without diabetes

Original Title

Resistance training attenuates circulating FGF-21 and myostatin and improves insulin resistance in elderly men with and without type 2 diabetes mellitus: A randomised controlled clinical trial

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Summary

Older men with or without diabetes did weight training for 12 weeks. The training lowered two body chemicals linked to fat and muscle problems and made muscles stronger. It also helped the body use insulin better—but only in men without diabetes.

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Surprising Findings

Resistance training improved insulin resistance only in non-diabetic elderly men, despite similar strength gains in both groups.

Many assume exercise improves insulin sensitivity universally, but this shows metabolic benefits may be limited once T2D is present.

Practical Takeaways

Elderly men should do resistance training 3 times per week at moderate intensity to improve muscle strength and metabolic hormone profiles.

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