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The Study

A Public Health Issue: Dietary Supplements Promoted for Brain Health and Cognitive Performance

In simple terms

This study is like checking what's really inside 12 different brain pills and comparing it to what's written on the label. It's NOT a test to see if the pills make you smarter - it's just checking if the ingredients match. The study found that most of the pills had ingredients missing or extra ingredients not listed. But it can't tell you if these pills actually help your brain or hurt it.

21%

Analysis score

21/ 100

Maximum 100 for a systematic review.

Where the score came from

Reporting0
Methodology1
Publication100
Statistical0
Study type (basis of the score)
Systematic Review
Level 2a - Systematic review of cohort studies
What’s the bottom line?

Researchers tested 12 popular brain-boosting supplements and found most contain ingredients not listed on the label.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Reviews of Cohort Studies
Level 2a
21

21 / 100

Quality score

Systematic reviews and meta-analyses of cohort studies. They sit above a single cohort study but below a single randomized trial, because the underlying evidence is still observational.

Cannot establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes - hidden ingredients could cause unexpected side effects or interactions with medications; consumers may not know what they're actually taking
  2. 283% of brain health supplements had unlisted ingredients; average 3.3 hidden ingredients per product; 67% were missing listed ingredients

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Journal of Alternative and Complementary Medicine

Year

2020

Authors

C. Crawford, Courtney Boyd, B. Avula, Yan-Hong Wang, I. Khan, P. Deuster

Open Access
32 citations
Analysis v5
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.