Why your whole wheat bread might block iron absorption

Original Title

Iron absorption in man: ascorbic acid and dose-dependent inhibition by phytate.

Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms

Summary

Phytate in whole grains like wheat can stop your body from absorbing iron, but vitamin C can help fix that.

Proposed Mechanism
Phytate inhibition of iron absorption via chelation
Verified
Ascorbic acid enhances iron absorption by reducing ferric to ferrous iron and preventing phytate chelation
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Quality Analysis
Methodology
40%
Moderate QualityOverall Score
Randomized Controlled TrialNutrition

Systematic Reviews & Meta-Analyses

Max 100

Randomized Controlled Trials

Max 90

Cohort Studies

Max 72

Case-Control Studies

Max 58

Cross-Sectional Studies

Max 44

Case Reports & Case Series

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Expert Opinion & Narrative Reviews

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StrongerWeaker
Randomized Controlled Trials
Level 1b
40

40 / 90

Evidence Score

Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.

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40%
Moderate QualityOverall Score

Publication

Authors

Hallberg L, Brune M, Rossander L