Mom's weak immune system during pregnancy can make her healthy baby more likely to get bad bacterial infections
Increased risk of serious bacterial infections due to maternal immunosuppression in HIV-exposed uninfected infants in a European country.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Even if babies don’t have HIV, if their mom had a weak immune system during pregnancy, the baby is more likely to get very bad bacterial infections in the first year.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
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Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Even if babies don’t have HIV, if their mom had a weak immune system during pregnancy, the baby is more likely to get very bad bacterial infections in the first year.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 552 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Publication
Authors
Taron-Brocard C, Le Chenadec J, Faye A, Dollfus C, Goetghebuer T, Gajdos V, Labaune JM, Perilhou A, Mandelbrot L, Blanche S, Warszawski J, France REcherche Nord&Sud Sida-HIV Hepatites - Enquete Perinatale Francaise - CO1/CO11 Study Group
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Claims (3)
If a mom with HIV has a weaker immune system during pregnancy, her baby — even if not infected with HIV — might be more likely to get serious bacterial infections in the first year of life, especially from certain types of bacteria.
Babies exposed to HIV but not infected have the same chance of getting serious viral infections in their first year, no matter how weak their mom's immune system was during pregnancy. This suggests mom's immune health might affect bacterial infections but not viral ones in these babies.
About 9 out of every 100 babies born to mothers with HIV—who don’t get infected themselves—still get very sick from infections in their first year, and nearly a quarter of those serious infections are caused by bacteria.