Can a shingles shot help prevent memory problems?

Original Title

595. The Effect of Herpes Zoster Vaccination on New Diagnoses of Dementia: A Quasi-randomized Study in Australia

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Summary

Scientists looked at people who were just barely old enough to get a free shingles shot and compared them to people who were just barely too old. Those who got the shot were less likely to be diagnosed with dementia later.

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Surprising Findings

The shingles vaccine was linked to reduced dementia—but not to any other chronic diseases or health behaviors.

Most people assume if a vaccine improves one health outcome, it’s because people are just generally healthier. But here, diabetes, heart disease, flu shots, and cancer screenings didn’t change—only dementia dropped.

Practical Takeaways

If you’re 65–79, get the shingles vaccine—even if you’ve had shingles before. This study suggests it may reduce your dementia risk.

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67%
Moderate QualityOverall Score

Publication

Journal

Open Forum Infectious Diseases

Year

2025

Authors

Michael Pomirchy, Christian Bommer, Pascal Geldsetzer

Open Access
Analysis v1