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The Study

The Women's Study for the Alleviation of Vasomotor Symptoms (WAVS): a randomized, controlled trial of a plant-based diet and whole soybeans for postmenopausal women

In simple terms

This study showed that women who changed their diet to eat mostly plants and soybeans felt better and had fewer hot flashes than women who didn’t change their diet. But it doesn’t prove the diet caused the improvement — it just makes it very likely.

60%

Analysis score

60/ 90

Maximum 90 for a randomized controlled trial.

Where the score came from

Reporting0
Methodology61
Publication100
Statistical77
Study type (basis of the score)
Randomized Controlled Trial
Level 1b - Individual RCT
What’s the bottom line?

Women who ate a plant-based diet with soybeans every day for 12 weeks had way fewer hot flashes and felt better overall.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Randomized Trials
Level 1b
60

60 / 100

Quality score

Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.

Can establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes — nearly 6 in 10 women stopped having disruptive hot flashes, and they felt better physically, emotionally, and sexually.
  2. 2Hot flashes dropped 79% overall, 84% for severe ones; 59% of women stopped having severe hot flashes; they lost 3.5 kg on average.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Menopause

Year

2021

Authors

Neal D. Barnard, Hana Kahleova, Danielle N. Holtz, Fabiola del Aguila, Maggie Neola, Lelia M. Crosby, Richard Holubkov

Open Access
Analysis v6

Related Content

Claims (8)

Assertion

Among postmenopausal women, a diet that includes whole soybeans and is low in fat led to 59% of participants no longer experiencing moderate-to-severe hot flashes after 12 weeks.

Quantitative
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Assertion

Postmenopausal women who ate 86 grams of cooked whole soybeans daily as part of a low-fat plant-based diet experienced an 88% reduction in moderate-to-severe hot flashes, while those who did not had a 34% reduction.

Quantitative
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Assertion

Postmenopausal women who eat 86 grams of cooked whole soybeans daily as part of a low-fat plant-based diet experience a 79% reduction in total hot flashes and an 84% reduction in moderate-to-severe hot flashes after 12 weeks.

Quantitative
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Assertion

Postmenopausal women who followed a low-fat, plant-based diet with 86 grams of cooked soybeans daily for 12 weeks experienced a 79% decrease in total hot flashes and an 84% decrease in moderate-to-severe hot flashes; 59% of them no longer had moderate-to-severe hot flashes.

Correlational
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Assertion

Postmenopausal women who follow a low-fat, plant-based diet and eat soybeans daily for 12 weeks experience greater reductions in nighttime moderate-to-severe hot flashes than those who make no dietary changes.

Causal
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Assertion

Postmenopausal women who follow a low-fat, plant-based diet with daily soybeans for 12 weeks experience lower symptom burden in vasomotor, psychosocial, physical, and sexual domains compared to those who make no dietary changes.

Causal
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