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The Study

Cross-sectional analysis of the reliability and engagement metrics of YouTube videos on semaglutide for weight loss

In simple terms

This study looked at 100 popular YouTube videos about a weight-loss drug and checked how well they explained the facts. It found that some videos were better than others, and that videos with more likes or comments weren’t necessarily the most accurate ones. But it didn’t watch what people actually did after watching the videos, so we can’t say the videos changed anyone’s behavior.

43%

Analysis score

43/ 44

Maximum 44 for a cross-sectional study.

Where the score came from

Reporting0
Methodology10
Publication100
Statistical77
Study type (basis of the score)
Cross-Sectional Study
Level 4 - Case series
What’s the bottom line?

Scientists looked at the top 100 YouTube videos about semaglutide (a weight-loss drug) to see if the most popular ones were also the most accurate.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Cross-Sectional & Case Series
Level 4
43

43 / 100

Quality score

Snapshots of a population at a single point in time, or descriptions of small groups. Can identify correlations and prevalence, but cannot determine cause and effect.

Cannot establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes — people are watching popular videos, but those videos often leave out important safety info, which could mislead viewers into thinking the drug is safer or more effective than it really is.
  2. 2Only 42% of videos mentioned side effects; 18% mentioned serious risks like thyroid cancer.
  3. 3Videos from doctors and hospitals scored much higher in quality than videos from regular people.
  4. 4More views didn't mean better info, but more likes and comments were slightly linked to better quality.
  5. 5Videos longer than 5 minutes were more accurate.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Medicine

Year

2026

Authors

Tuğba Güler Sönmez, Izzet Fidancı

Open Access
Analysis v5
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.